Transient global amnesia with a hippocampal lesion followed by transient epileptic amnesia

Transient epileptic amnesia (TEA) is a seizure disorder characterized by brief, recurrent attacks of amnesia in middleaged or elderly subjects, often occurring on waking, with favorable response to anticonvulsant medication [1]. While this syndrome is becoming increasingly recognized, its association with transient global amnesia (TGA) is not fully understood. It remains unknown whether TEA is a separate entity from recurrent TGA, or whether TGA can be a cause of TEA. We report a patient initially presenting with TGA and a hippocampal lesion on magnetic resonance imaging (MRI), followed by TEA episodes, suggesting that this damaged region associated with TGA may be an epileptic focus resulting in TEA.